Overview
- University of Osaka researchers threaded ultra‑thin wire electrodes through cortical and deep veins in pigs to record brain activity with fidelity comparable to traditional intracranial methods.
- Intravascular stimulation of the motor cortex elicited muscle responses in the face and shoulders, demonstrating both recording and stimulation capability.
- The approach targets vessels rather than brain tissue, presenting a potential alternative to craniotomy or penetrating depth electrodes for high‑resolution monitoring.
- Authors highlight prospective uses in epilepsy evaluation and future brain‑computer interfaces for severely paralyzed patients, though the work remains preclinical with no human data reported.
- The peer‑reviewed study, titled “Microendovascular Neural Recording from Cortical and Deep Vessels with High Precision and Minimal Invasiveness,” appears in Advanced Intelligent Systems (DOI: 10.1002/aisy.202500487).