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Casgevy Launch Stumbles, Yet Analysts Eye Upside for CRISPR Therapeutics

RBC raised its target to $50 after a weak quarter, with Vertex projecting more than $100 million in 2025 sales.

Overview

  • RBC Capital lifted its CRISPR Therapeutics price target to $50 and kept a Sector Perform rating after third-quarter underperformance.
  • RBC noted Casgevy revenue of $17 million in Q3 versus a $41 million consensus estimate, and reported infusions fell to 10 from 16 in Q2.
  • Vertex projects over $100 million in total Casgevy revenue for 2025, which RBC interprets as more than $39 million in expected Q4 sales.
  • Yahoo Finance data show an average price target of $82.41, implying roughly 58% upside, even as the stock fell about 23% over the past month.
  • Citizens reiterated an $86 target, highlighting Phase 1 CTX310 data with significant reductions in circulating ANGPTL3 that support the in‑vivo program.