Overview

• Kickoff is 4:05 p.m. ET at State Farm Stadium on CBS, with streaming available on Paramount+.
• Arizona enters 2-2 after consecutive late losses to division foes, while Tennessee is 0-4 following a 26-0 shutout last week.
• The Cardinals' backfield is depleted with James Conner out for the season and Trey Benson on IR, leaving Michael Carter and Emari Demercado to share carries behind a banged-up line.
• Sportsbooks list Arizona at -7.5 with a total around 41.5 points, and several previews project the Cardinals to cover.
• Arizona has won three straight in the series and leads 8-4 overall, and three Titans — Kyzir White, Carlos Watkins and Darrell Baker — previously spent time with the Cardinals.