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Cardinals Expect Kyler Murray to Sit vs. Colts as Jacoby Brissett Prepares to Start

Arizona is opting for caution with Murray’s mid-foot sprain, a Lisfranc-type injury that could extend his absence.

Overview

  • Multiple outlets report Murray is unlikely to play in Week 6 at Indianapolis, with Arizona preparing Jacoby Brissett to start while leaving a final call for Sunday morning.
  • NFL Network reports Murray’s injury is a mid-foot, Lisfranc-type sprain that could cost him more than one game if aggravated, aligning with a rest window before a Week 8 bye.
  • The Cardinals promoted Kedon Slovis to the active roster for depth, placed punter Blake Gillikin on injured reserve with a back injury, and signed veteran Pat O'Donnell.
  • Arizona will also be without defensive linemen Darius Robinson (pectoral) and Bilal Nichols (personal), as Indianapolis enters 4-1 behind Daniel Jones’ career-best efficiency and Jonathan Taylor’s league-leading rushing pace.
  • Kickoff is 1:00 p.m. ET on FOX with local telecasts in Indiana and Arizona, and inactives will be confirmed 90 minutes before the game.