Overview

• California residents can now directly purchase naloxone nasal spray through the CalRx program for $24 per two-pack, approximately half the market price.
• This expansion marks a shift from institutional-only access to individual consumer availability, enhancing accessibility statewide.
• The CalRx initiative, funded by $150 million in opioid settlement dollars, has distributed over 6 million naloxone kits since 2018, reversing 355,000 overdoses.
• Preliminary data shows a decline in synthetic opioid overdose deaths in 2024, the first such decrease since 2018, attributed to comprehensive intervention efforts including naloxone distribution.
• While naloxone access progresses, the CalRx insulin manufacturing project remains delayed, with no set timeline for rollout.