Overview
- State health authorities reported three clade I mpox infections in Long Beach and Los Angeles County with no recent international travel, indicating likely person-to-person transmission.
- All three patients were hospitalized and are now recovering, and the California Department of Public Health says the overall risk to the public remains low.
- Officials advise at-risk individuals to receive both doses of the Jynneos vaccine and recommend that exposed persons get vaccinated before symptoms and avoid intimate contact for 21 days.
- Clade I is associated with more severe illness, particularly for people with weakened immune systems, and health agencies urge testing and home isolation until rashes fully heal.
- Separate reporting highlights Australia’s sharply lower 2025 caseload compared with 2024, attributed to targeted vaccination and behavior change, while a conservative watchdog in the U.S. calls for more blunt, venue-specific messaging.