Overview

• Latest fission yeast experiments reveal caffeine activates AMPK, a cellular energy gauge conserved across species
• This activation influences cell growth regulation, DNA repair efficiency and stress response pathways tied to aging
• The study updates earlier findings by showing caffeine acts on AMPK rather than directly on the TOR growth regulator
• Since metformin also targets AMPK, these results suggest shared mechanisms that could inform anti-aging therapies
• Researchers caution that benefits depend on moderate caffeine consumption to avoid potential adverse effects