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BYU’s Elite Defense Heads to Boulder in Defining Test for Deion Sanders’ Colorado

The unbeaten Cougars’ visit is widely viewed as a measuring stick for Colorado’s postseason ambitions.

Colorado Buffaloes quarterback Kaidon Salter (3) carries the ball for a touchdown in the fourth quarter against the Wyoming Cowboys at Folsom Field. Mandatory Credit: Ron Chenoy-Imagn Images
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Sep 20, 2025; Boulder, Colorado, USA; Colorado Buffaloes head coach Deion Sanders before the game against the Wyoming Cowboys at Folsom Field. Mandatory Credit: Ron Chenoy-Imagn Images

Overview

  • Colorado sits at 2-2, and another conference loss would undercut Big 12 title hopes and even bowl eligibility, according to USA TODAY’s assessment.
  • BYU arrives unbeaten and ranked with one of the nation’s top defenses, and early lines positioned the Cougars as roughly a 6.5-point favorite.
  • Liberty transfer Kaidon Salter is the undisputed starter after a breakout win over Wyoming, ending the Buffaloes’ early-season quarterback rotation.
  • Deion Sanders signaled heightened urgency, saying he was “rough” on players and staff in practice ahead of Saturday night’s ESPN game at Folsom Field.
  • Colorado’s run defense ranks 121st nationally and now faces BYU running back LJ Martin, a top-10 rusher who scored twice against the Buffs in last year’s Alamo Bowl.