Overview
- Argentina’s week 42 National Epidemiological Bulletin reports 2025 pertussis infections have tripled versus 2024, with 63 confirmed and 252 probable cases counted to week 40.
- The Province of Buenos Aires activated an epidemiological alert and pediatric societies issued guidance after four deaths in infants aged one month to two years were confirmed.
- Officials note three of the deceased infants were unvaccinated and one newborn lacked protection because the mother was not vaccinated during pregnancy.
- Clinical guidance urges treating suspected cases with a five‑day azithromycin course, providing antibiotic prophylaxis to close contacts, checking and updating vaccination status, and keeping schoolchildren under seven at home until five days of adequate antibiotic therapy are completed.
- Experts link the resurgence to lower vaccine uptake, waning immunity, and pandemic disruptions, and other jurisdictions such as Mendoza have issued alerts to reinforce surveillance and vaccination despite no active local outbreak.