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Bryan Johnson Live-Streams High-Dose Psilocybin Test for Longevity, Says Experience Changed Him

He ran the five-gram session to capture extensive biomarker data within his anti-ageing regimen, with results still pending.

Overview

  • Johnson ingested five grams of psilocybin mixed with orange juice and broadcast the session on X as Blueprint co‑founder Kate Tolo documented it in real time.
  • The team collected samples and readings during the trip, including a saliva vial, a brain scan, blood pressure and an adrenal stress profile, with a stated plan to test 240 biomarkers.
  • Tolo reported a warped sense of time and visual hallucinations, while Johnson later posted that he felt “so happy to be alive” and that the experience had changed him.
  • He described the approach as “casting a really wide net” to see whether any measures indicate rejuvenation or longevity effects, and he continued his routine testing afterward.
  • No formal analysis has been released, and Johnson said he would share more after taking a few days to reflect, with one account noting he planned monthly sessions over three months.