Overview
- People who achieved prediabetes remission had a 58% lower risk of cardiovascular death or hospitalization for heart failure.
- Heart attack, stroke and other major adverse cardiovascular events were 42% less likely in those reaching remission.
- The reanalysis harmonized data from DPPOS in the US (~20 years) and DaQingDPOS in China (~30 years), covering more than 2,400 participants.
- Benefits were consistent across both countries and persisted for decades, even when weight loss was similar in those who did not normalize glucose.
- Researchers propose adopting sustained glucose normalization as a measurable prevention target, using a fasting glucose threshold of ≤97 mg/dL.