Overview
- Production for Season 2 began in late July in Toronto, bringing the series back to its Bronx General Hospital setting
- NBC has slated the sophomore run to debut Monday, September 22 at 10 p.m. ET as the first scripted entry in its 2025–26 fall lineup
- Zachary Quinto will reprise his role as Dr. Oliver Wolf, the larger-than-life neurologist at the heart of the Oliver Sacks–inspired drama
- Al Calderon, Brian Altemus and John Clarence Stewart join the main cast as key medical staff while Bellamy Young appears in a recurring role
- Season 1’s acclaim for its immersive neurological visuals and focus on patient advocacy secured its renewal for a second season