Overview

• The saliva test identified more aggressive prostate cancers and reduced false positives compared to the PSA blood test, according to a study involving 6,300 UK men aged 55 to 69.
• Researchers estimate the test could detect up to 12,350 cases earlier and save the NHS approximately £500 million annually by avoiding unnecessary treatments.
• The UK National Screening Committee is reviewing the test’s potential for national screening, with further trials planned to validate its effectiveness across diverse populations.
• The test saved lives in trial cases, including two brothers whose aggressive prostate cancers were missed by traditional methods but detected through the genetic risk assessment.
• While promising, experts urge caution regarding overdiagnosis risks and emphasize the need for evidence-based decisions before implementing a national screening program.