Breakthrough in Understanding Stress-Induced Memory Changes

Researchers uncover how stress alters memory precision, offering potential PTSD treatment insights.

Stress increases endocannabinoid levels, disrupting neurons that maintain memory specificity.
This disruption leads to enlarged memory engrams, causing generalized and aversive memories.
Blocking endocannabinoid receptors on specific neurons restored memory precision in preclinical models.
The study, conducted on mice, highlights potential therapeutic avenues for PTSD and stress-related disorders.
Researchers also noted similarities in memory processing between stressed adult brains and developing brains.