Breakthrough in Breast Cancer Research: Pathway to Prevent Relapse Discovered

Scientists identify enzyme inhibition as a key to stopping 'hibernating' cancer cells, offering hope for future treatments.

Researchers have discovered that breast cancer cells can 'hibernate' to evade treatment, potentially causing relapse years later.
The study focused on hormone therapies for oestrogen receptor positive (ER+) breast cancer, which constitutes 80% of all breast cancers.
Inhibiting a specific enzyme, G9a, prevents cancer cells from becoming dormant and kills cells already in hibernation.
This breakthrough offers new hope for developing treatments that prevent breast cancer from returning.
The research, funded by Cancer Research UK, was published in the journal Cancer Discovery.