Breakthrough Discovery Reveals Brain Circuit Behind Placebo-Induced Pain Relief

Researchers identify a neural pathway linking the cingulate cortex, pons, and cerebellum, offering new insights into pain management.

Scientists from UNC, Stanford, and other institutions mapped a brain circuit responsible for the placebo effect in pain relief.
The pathway involves neurons in the anterior cingulate cortex projecting to the pontine nuclei and cerebellum.
Activation of this neural circuit can induce pain relief even without actual medication.
Findings suggest potential new treatments for chronic pain that avoid harmful side effects and addiction.
The study provides a framework for exploring other mind-body interactions and placebo effects.