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16h ago

Brazil Sets Jan. 18 Start for Single-Dose Dengue Vaccination in Three Cities

Health officials will use rapid, age-phased campaigns to reach roughly half of residents in each site to measure real-world protection.

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Overview

  • The Ministry of Health selected Botucatu (SP), Maranguape (CE) and Nova Lima (MG) for accelerated mass immunization using the Butantan-DV vaccine.
  • Local drives begin on January 18 with primary health workers, then proceed by descending age groups down to 15 to enable impact assessment at community scale.
  • Butantan-DV is the first single-dose dengue vaccine, approved by Anvisa for ages 12 to 59, with trial data reporting ~75% efficacy against symptomatic disease, >91% against severe cases and 100% against hospitalizations.
  • Instituto Butantan plans to deliver about 1.3 million doses by the end of January under a federal contract worth R$368 million for an initial 3.9 million doses.
  • The national program will also use the two-dose QDenga for ages 10 to 14 nationwide with 9 million doses ordered, while current guidance excludes people 60+, pregnant individuals and the immunocompromised.