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Brain Care Score Predicts Stroke Risk, With Larger Relative Gains for Black Adults

Researchers report the lifestyle-based score tracks with lower stroke incidence over nearly 16 years in a 10,861-person U.S. cohort.

Overview

  • The Mass General Brigham analysis, published December 18 in Neurology, examined stroke-free Black and white adults aged 45 and older from the REGARDS study.
  • A five-point higher Brain Care Score correlated with a 53% lower stroke risk in Black participants and a 25% lower risk in white participants after demographic and socioeconomic adjustments.
  • The 0–21 score consolidates physical, lifestyle, and social-emotional factors such as blood pressure, blood sugar, nutrition, alcohol use, sleep, exercise, stress, and social relationships.
  • Investigators frame the score as a practical primary care tool to identify modifiable behaviors and target prevention, with potential to help address racial stroke disparities.
  • Authors caution the findings are observational and do not prove causality, and they call for intervention and implementation studies; the work was supported by NIH and the American Heart Association.