Overview

• Creators including YouTuber NickTew showcased a combo using a Vampiric Vivisecting Throwing Knife with the Penetrator Augment and Vex’s Bloodletter and Contamination passives to create a self-perpetuating bleed loop.
• Demonstrations show bosses melting in seconds and even being effectively one-shot on Ultimate Vault Hunter Rank 5, with damage numbers reaching into the billions.
• NickTew achieved the effect with only 15 skill points invested, indicating the build requires minimal setup and could scale further with optimization.
• PC Gamer reports the Penetrator effect functions regardless of the knife’s item level, while players note the knife is a rare drop and point to Splashzone as a farm spot.
• NickTew cautions the interaction may fail in co-op if more than one player uses the knife, and Gearbox’s Graeme Timmins says the team is investigating potential stability issues without making a knee-jerk change.