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Biotech Firm Creates Genetically Edited 'Woolly Mouse' to Advance Mammoth Revival Efforts

Colossal Biosciences has engineered mice with mammoth-like traits, marking a significant step in its controversial quest to de-extinct the woolly mammoth by 2028.

  • The 'woolly mouse' was developed by editing seven genes to give the rodents mammoth-like features, including long, wavy, golden fur and altered fat metabolism traits.
  • Colossal Biosciences aims to use similar genetic techniques to create mammoth-like Asian elephants, with a goal of producing the first calf by 2028.
  • Scientists used ancient mammoth DNA to identify key genes for cold adaptation and tested their viability in mice due to their short gestation period and established genetic research history.
  • Critics question the ecological, ethical, and financial implications of de-extinction, arguing resources might be better spent on conserving existing species and habitats.
  • The project has raised over $435 million and aims to develop technologies with broader applications in conservation and biotechnology, including artificial wombs and tools for endangered species preservation.
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