Particle.news

Download on the App Store

BioCog Tablet Test Sharpens Primary Care Detection of Cognitive Impairment Linked to Alzheimer’s

The self‑administered battery is intended to triage patients in general practice for phosphorylated‑tau blood testing.

Overview

  • A Nature Medicine study from Lund University introduces BioCog, a brief tablet‑based cognitive assessment designed for use in primary care.
  • In a primary‑care cohort, BioCog reached 85% accuracy with a single cutoff versus 73% for physicians, rising to about 90% with dual cutoffs.
  • The test evaluates memory, attention, orientation, delayed recall and recognition while capturing timing metrics not feasible with paper tools.
  • Combining BioCog results with plasma phosphorylated‑tau assays increased accuracy for identifying Alzheimer’s pathology.
  • Researchers tested two cohorts of 223 and 403 patients and note that blood biomarker access remains concentrated in specialist clinics, with careful use advised to avoid false positives in subjective cognitive decline.