Overview
- New Orleans (0-3) visits Buffalo (3-0) on Sunday at 1 p.m. ET on CBS, with the Bills riding a 13-game regular-season home winning streak.
- Buffalo officially ruled out DT Ed Oliver (ankle) and LB Matt Milano (pectoral), while RT Spencer Brown (calf) and DE A.J. Epenesa (pectoral) are questionable.
- Saints head coach Kellen Moore ruled out DE Chase Young (calf) and OL Dillon Radunz (toe); WR Devaughn Vele (hip) is questionable.
- New Orleans expects its full starting offensive line for the first time this season, with Trevor Penning at left guard and Taliese Fuaga returning at right tackle.
- Oddsmakers list Buffalo as a heavy favorite (spread around 15.5–16.5), with analysis pointing to the Saints leaning on the run against the Bills’ bottom-ranked rush defense.