Overview
- Keon Coleman was not listed on the injury report and will miss his third game of the season.
- NFL Media's Cameron Wolfe reported the Week 16 deactivation was solely the coach's call.
- Mecole Hardman, activated from injured reserve this week, is active for Buffalo.
- The Bills can clinch a playoff berth with a win plus a loss by either the Texans or the Colts, strengthening their push for a sixth straight AFC East title.
- Buffalo's other inactives include WR Gabe Davis, DT Jordan Phillips, K Matt Prater, OL Tylan Grable, DB Darnell Savage, and DT Larry Ogunjobi.