Overview

• The Buffalo Bills (4-2) are looking to deny New England Patriots' head coach Bill Belichick his 300th career win and to secure their fifth consecutive win against the Patriots.
• Buffalo's key player to watch is RB James Cook, who is expected to take on a bigger role as the Patriots' strategy involves limiting the Bills' top threat, receiver Stefon Diggs.
• Despite having a sore right shoulder, Bills QB Josh Allen is anticipated to play. He has won six of the last seven games against the Patriots, including achieving a touchdown pass in 14 straight outings.
• The Bills lead the NFL with 24 sacks this season and their opponents have managed to convert only 32 of 76 third down attempts in their six games so far.
• The Patriots (1-5) aim to recover from their disappointing start of the season, with key player WR Kendrick Bourne leading the team in catches (28) and receiving yards (307).