Overview
- Kickoff is 8:20 p.m. ET on NBC at Highmark Stadium, where Buffalo enters 4-0 and New England arrives 2-2.
- Sportsbooks list the Bills around -8 to -8.5 with a total near 49.5, and CBS Sports’ SportsLine AI projects Buffalo to cover.
- The matchup spotlights Buffalo’s league-leading rushing attack behind James Cook (401 yards, five TDs) against a Patriots defense allowing 77.5 rushing yards per game.
- Josh Allen is drawing MVP talk with seven touchdown passes to one interception plus three rushing scores, and Mike Vrabel praised his “immense talent.”
- Buffalo owns the NFL’s fewest passing yards allowed per game, special teams could swing field position with Marcus Jones, and this is New England’s final regular-season visit to Highmark before the Bills move venues.