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Bills Host Patriots on Sunday Night Football as Odds Favor Buffalo

Buffalo’s high-output offense meets New England’s elite run defense in the teams’ last regular-season game at Highmark Stadium.

Overview

  • Kickoff is set for 8:20 p.m. ET at Highmark Stadium on NBC and Peacock.
  • Buffalo enters 4-0 and New England 2-2, with the Bills positioned to strengthen their early AFC East lead.
  • Sportsbooks list Buffalo around -8 to -8.5 with a money line near -424, and SportsLine’s AI projects a comfortable Bills cover with an average 34-19 outcome.
  • Buffalo averages 404 yards and 33.3 points per game with a league-leading ground attack, while New England owns a top-tier rush defense allowing roughly 77.5 rushing yards per game.
  • The Patriots have dominated prime-time meetings against Buffalo at 9-2 overall and 4-0 on Sunday Night Football, and this marks New England’s final regular-season visit before the Bills move to a new venue next year.