Overview
- Kickoff is 8:15 p.m. ET at Highmark Stadium in Orchard Park, with exclusive national streaming on Amazon Prime Video featuring Al Michaels, Kirk Herbstreit and Kaylee Hartung.
- Buffalo enters 2-0 and Miami 0-2, and Josh Allen is 13-2 in his career against the Dolphins.
- Betting markets list the Bills as roughly a double-digit favorite, including lines around Buffalo -12.5 and a total near 49.5.
- The Bills will be without Ed Oliver and Matt Milano, with Taron Johnson, Shaq Thompson and Cam Lewis among additional questionables, while Miami has RT Austin Jackson on IR, Darren Waller out and Jaylen Waddle questionable with a shoulder issue.
- James Cook has opened with 176 rushing yards and three touchdowns, drawing attention as a key matchup against a Miami defense that has allowed at least 122 rushing yards in each of its first two games.