Overview
- Kickoff is Sunday, Nov. 16 at 1 p.m. ET at Highmark Stadium in Orchard Park on CBS, with streaming on Paramount+.
- Sportsbooks price Buffalo around -5.5 with a total near 46.5, while SportsLine’s model leans Buccaneers against the spread even as the Bills win most simulations.
- Buffalo ruled out tight end Dalton Kincaid, and Tampa Bay ruled out running back Bucky Irving with a shoulder injury, shifting attention to Dawson Knox and the Bucs’ rushing options.
- Rookie wideout Emeka Egbuka is a featured Tampa Bay threat, leading first-year players in receiving yards and touchdowns and entering the week as an Offensive Rookie of the Year favorite.
- Recent form and matchups spotlight Buffalo’s strong home record and shaky run defense, with Josh Allen meeting fellow 2018 draftee Baker Mayfield after playful pregame jabs.