Overview
- Kickoff is Sunday, Sept. 28 at 1 p.m. ET at Highmark Stadium, with the game on CBS and streaming options including Paramount+ and Fubo.
- Buffalo enters 3-0 and seeks its first 4-0 start since 2020, while New Orleans is 0-3 after a 44-13 loss to Seattle.
- BetMGM lists the Bills as 16.5-point favorites, with Buffalo 2-1 against the spread and the Saints 0-3.
- Josh Allen has 755 passing yards and five touchdowns without a turnover through three games, and the Bills have won 13 straight regular-season home games.
- Injury watch includes Bills DT Ed Oliver (ankle) and LB Matt Milano (pectoral) listed as questionable, Saints RT Taliese Fuaga (knee/back) and DL Chase Young (calf) uncertain, and Bills RT Spencer Brown’s calf to be monitored.