Overview

• Buffalo visits Atlanta on Monday, Oct. 13 at 7:15 p.m. ET on ESPN from Mercedes‑Benz Stadium with Chris Fowler, Louis Riddick, Dan Orlovsky, Katie George and Peter Schrager on the call.
• BetMGM lists the Bills as roughly a 4-point favorite (moneyline Buffalo -200, Atlanta +165) with a total near 48.5.
• SportsLine’s simulations project Buffalo to win nearly 80% of the time and cover in well over 70% of scenarios, while ESPN’s matchup tool gives the Bills a 60.7% win probability.
• Following multiple Week 5 stunners, including Buffalo’s loss to New England and Denver’s win over Philadelphia, analysts caution that survivor pools and Week 6 lines carry elevated uncertainty.
• Beyond Bills-Falcons, models and handicappers spotlight Dallas and Tampa Bay as potential spread plays, and several favorites — including the Chiefs and 49ers in their matchups — are on various upset-alert lists, with a Monday night doubleheader also on tap.