Overview

• Kickoff is 7:15 p.m. ET at Mercedes-Benz Stadium on ESPN, with the 4-1 Bills visiting the 2-2 Falcons.
• Sportsbooks list Buffalo as a short favorite (about -3.5 to -4.5) with a total near 49.5–50, public money leaning Bills and several models split on the spread and total.
• Buffalo placed Damar Hamlin and rookie T.J. Sanders on IR; Matt Milano is out, tight end Dalton Kincaid and receiver Curtis Samuel are inactive, and defensive tackle Ed Oliver is expected to return.
• Atlanta gets cornerback A.J. Terrell back; wideout Darnell Mooney is out, and defensive back Clark Phillips III and safety Billy Bowman Jr. are inactive.
• Josh Allen pilots a top-three offense in yards and points, while Bijan Robinson’s workload looms large against a Bills run defense allowing 145.6 rushing yards per game.