Overview
- The game kicks off at 8:15 p.m. ET Monday at SoFi Stadium in Inglewood with the Rams installed as 3.5-point favorites and the over/under set at 54.5.
- Rams coach Sean McVay confirmed Aaron Donald is cleared to play and Puka Nacua is active, restoring key pass-rush and receiving weapons for Los Angeles.
- Buffalo will be without defensive tackle Ed Oliver and receiver Joshua Palmer for the game, and D.J. Moore is listed questionable, changes that weaken the Bills’ lineups on both sides of the ball.
- Betting markets and simulation models are split: some experts and handicappers expect a high-scoring quarterback duel while SportsLine-style simulations and other models favor the Under.
- The matchup is framed as a possible Super Bowl preview because it pits recent MVPs Josh Allen and Matthew Stafford against one another and recalls a 44-42 meeting in 2024 that set shootout expectations.