Overview

• Berlin has recorded 43 Mpox cases in 2025 as of March 23, a fourfold increase compared to the same period in the previous two years.
• The outbreak is characterized by local transmission, with no recent travel history reported among infected individuals.
• Men, with an average age of 34, account for all reported cases; seven cases are believed to have been transmitted through sexual contact.
• Half of the 2025 cases involve individuals who had received at least one Mpox vaccine dose, highlighting concerns about vaccine efficacy against the Clade Ib variant.
• Public health authorities warn of potential spread at large events and festivals and are offering free vaccinations, including for uninsured individuals, at designated health centers in Berlin.