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Beetroot Juice Lowers Blood Pressure in Seniors by Altering Oral Microbiome

Researchers intend to launch larger trials focused on demographic influences on nitrate conversion through oral bacteria.

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Overview

  • The University of Exeter trial found that seniors consuming nitrate-rich beetroot juice for two weeks experienced significant drops in 24-hour systolic and diastolic blood pressure compared to a nitrate-stripped placebo.
  • Gene sequencing of mouth swabs revealed that older adults showed marked declines in inflammatory Prevotella and increases in beneficial nitrate-metabolizing Neisseria after juice intake.
  • The study confirms that oral bacteria convert dietary nitrates into nitric oxide, a vasodilator that widens arteries and lowers blood pressure more effectively in older adults.
  • Earlier meta-analyses from 2017 and 2022 established consistent blood pressure reductions with daily beetroot juice, with the largest effect seen at 250 mL doses.
  • Researchers recommend larger, nuanced trials to examine demographic and lifestyle influences on nitrate response and to test other nitrate-rich vegetables like spinach and celery.