Overview
- University of Exeter scientists ran a randomized, placebo-controlled crossover study with 75 participants who completed two-week phases of nitrate-rich beetroot juice and a nitrate-removed placebo separated by a washout.
- Older adults in their 60s and 70s recorded measurable blood pressure reductions during the nitrate phase, with no change during the placebo phase.
- Oral swab sequencing in older participants showed fewer Prevotella and more Neisseria after nitrate intake, consistent with enhanced conversion of dietary nitrate to nitric oxide.
- Younger adults saw microbiome changes but no blood pressure benefit, indicating an age-related difference in response.
- Experts note that nitrate-rich vegetables such as beets and leafy greens can support vascular health but advise against replacing prescribed hypertension treatment, underscoring the need for larger trials.