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Argentina’s Syphilis Cases Up 20% in 2025 as Notifications Near 2024 Record

Health officials are expanding rapid testing and penicillin distribution in response to falling condom use and reinfections.

Overview

  • The national surveillance bulletin reports 36,702 syphilis notifications in the first 44 epidemiological weeks of 2025, a 20.5% year‑on‑year increase for the same period.
  • Argentina set a record 36,917 cases in 2024, and the notification rate rose from 56.1 per 100,000 in 2019 to 93 in 2024, a 65.8% jump.
  • Young people carry most of the burden, with 76% of cases in those aged 15–39 and the highest rates in the 20–24 and 25–29 groups, where women outpace men.
  • Growth is uneven: Córdoba has the highest provincial rate at 220.3 per 100,000, with sharp 2025 rises in Neuquén (+110%), Entre Ríos (+72%) and Tierra del Fuego (+57%), while Santa Fe shows a slight decline (−2%).
  • Experts link the surge to reduced condom use and lower risk perception tied to HIV treatment/PrEP, and an AHF survey found about 28% of male cases were reinfections; the Health Ministry is reinforcing surveillance and updated perinatal protocols in May 2025.