Overview

• Resolution 2214/2025 makes digital prescribing compulsory in outpatient settings for medications, medical supplies, diagnostic studies, procedures and devices
• Health professionals must secure unique prescription keys within 45 days, adapt archived‐medication systems in 90 days and integrate restricted-substance orders in 120 days
• Registered digital platforms are required to retain controlled and archived prescriptions for at least three years to facilitate state monitoring and ANMAT auditing
• Paper prescriptions will remain valid temporarily in areas without reliable internet access while Tucumán targets a complete paper-free transition within 60 days
• Provinces with existing e-prescribing systems, including Buenos Aires, will align their platforms with national interoperability standards under the new mandate