Overview
- Pachuca rallied to beat Cruz Azul 2-1 in the first leg behind a Charlyn Corral brace, leaving La Máquina needing a two-goal win on Saturday in Hidalgo to overturn the series.
- Tigres edged Juárez 1-0 on a Stephany Mayor header, taking a one-goal cushion back to El Volcán after finishing the regular season as top seed with 42 points.
- Monterrey and América drew 1-1, with Irene Guerrero scoring from the spot and Jermaine Seoposenwe equalizing in stoppage time; América advances with any aggregate draw, so Rayadas must win the return.
- Chivas and Toluca finished 2-2 as Alicia Cervantes scored twice for Guadalajara and Faustine Robert answered with a brace for the Diablas, leaving Toluca protected by the higher-seed tiebreak.
- The two-leg format sends tied aggregates to the higher regular-season finisher, and second legs this weekend (Nov 8–9) on Canal 9, TUDN, ViX, YouTube, Prime Video, Tubi and Fox will decide the semifinalists.