Overview

• Dana-Farber researchers presented ASCO data from over 1,600 stage III colon cancer patients treated in the CALGB/SWOG80702 trial.
• Investigators applied the EDIP score to measure dietary inflammation and found the most proinflammatory diets were linked to an 87% higher risk of death.
• Patients combining anti-inflammatory diets with high physical activity experienced a 63% lower mortality risk compared to those with proinflammatory diets and low activity.
• Analysis revealed that celecoxib use did not alter the association between diet and survival, indicating an independent effect of dietary patterns.
• Researchers plan further studies to develop tailored dietary guidelines and explore the biological mechanisms behind inflammation’s impact on cancer progression.