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Anterior Temporal Lobe Anchors Social and Emotional Judgments, Anxiety Alters Its Integration

Moving to complete fine-grained connectivity analyses of the ATL, researchers are securing a balanced sample to assess how gender and sleep quality shape network dynamics.

Overview

  • Specialized fMRI techniques addressed previous imaging distortions to pinpoint strong upper-ATL involvement in interpreting social hierarchies and reading emotional facial expressions.
  • Preliminary data show individuals with subclinical anxiety exhibit heightened upper-ATL activity and reduced coordination between semantic and emotional processing systems.
  • A July 2025 Sleep Medicine paper reports that individual sleep quality moderates functional connectivity patterns linked to sensitivity to punishment and reward.
  • Researchers are mapping both functional and structural ATL connections, including the uncinate fasciculus linking the ATL to the orbitofrontal cortex, to clarify pathways underlying anxiety and guilt.
  • The team is recruiting a gender-balanced sample to ensure accurate evaluation of demographic influences on ATL network function.