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Androgen receptor gene variants shape domestic cat purring and aggression

Kyoto University team will expand comparisons to wild relatives to deepen understanding of cat behavior for improved welfare.

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Overview

  • Researchers at Kyoto University’s Wildlife Research Center analyzed DNA from 280 mixed-breed pet cats alongside owner-assessed behaviors to examine androgen receptor gene variants.
  • Cats carrying the short-type allele scored higher for purring and, in males, vocalized more toward humans, while short-type females exhibited increased stranger-directed aggression.
  • Comparison with 11 wild Felidae species showed that wild cats possess only the short-type variant, whereas domestic cats also carry long-type alleles likely arising through domestication and selective breeding.
  • These genetic-behavior links offer a basis for veterinarians and owners to predict tendencies and tailor care strategies according to a cat’s androgen receptor profile.
  • The research team plans to extend their analysis to other wild feline species to further unravel evolutionary influences on social and communicative behaviors.