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Androgen Receptor Gene Variants Drive Purring and Vocal Behavior in Domestic Cats

The study highlights a genetic basis for feline social signals with potential to guide targeted animal welfare strategies

Stock image of a purring cat
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Overview

  • Researchers published their findings in PLOS One after analyzing androgen receptor gene variants and owner-reported behaviors in 280 mixed-breed cats in Japan
  • Cats carrying the short-type androgen receptor allele exhibited higher purring intensity and increased vocalizations toward humans, especially among males
  • Female cats with the short-type variant demonstrated elevated stranger-directed aggression, revealing sex-specific genetic effects on social behavior
  • Comparisons with 11 wild Felidae species showed that domestic cats uniquely possess longer androgen receptor gene variants absent in their wild relatives
  • The research team plans to extend their genetic and behavioral analyses to additional feline species to uncover evolutionary drivers of cat sociability