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Amy Schumer Thanks Fans After Las Vegas Photo Shows Noticeable Weight Loss

Schumer credits recent progress to Mounjaro with hormone therapy following an earlier, intolerable reaction to Ozempic.

Overview

  • On October 4, the 44-year-old shared an Instagram photo from a Las Vegas outing with Alex Saks and Jillian Bell, wearing a Miu Miu mini shirt dress and heels that revealed a visibly slimmer figure.
  • Celebrities flooded the comments with praise, including Margaret Josephs, Lee Daniels, Chelsea Handler, Amy Sedaris, Isla Fisher, and Georgia Louise, many highlighting her legs.
  • She engaged with the reaction by replying, “Loving the love. My legs thank you!” and reposting a close-up with the caption, “Don’t call it a comeback.”
  • Schumer has said Ozempic/Wegovy made her bedridden and nauseated, attributing the response to GDF15-related sensitivity despite rapid weight loss.
  • In March, she reported good results using Mounjaro alongside estrogen and progesterone after earlier liposuction in 2022, and she is recovering from an August L5 laminectomy.