Overview
- Self-collected vaginal samples are now an acceptable option for primary HPV screening, though clinician-collected cervical specimens remain preferred.
- When a self-collected test is HPV-negative, repeat screening is recommended in three years; clinician-collected primary HPV testing continues on a five-year schedule.
- Average-risk individuals should start screening at age 25 and may exit at 65 after negative primary HPV or co-tests at ages 60 and 65, or after three consecutive negative cytology tests if HPV testing is not available.
- The FDA has authorized multiple self-administered options, including an at-home kit from Teal Health that uses a mailed vaginal swab with provider oversight.
- ACS says the changes aim to raise screening uptake and reduce disparities, while USPSTF still begins routine HPV screening at 30 and may incorporate self-collection in future updates according to reporting.