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AMD Launches Instinct MI350 GPUs to Challenge Nvidia’s Blackwell Line

Adopted by leading cloud providers, the MI350 series marks AMD’s bid to narrow the gap with Nvidia as it prepares its Helios rack architecture.

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Lisa Su, CEO of AMD, attends the Artificial Intelligence (AI) Action Summit at the Grand Palais in Paris, France, February 10, 2025. REUTERS/Benoit Tessier/File Photo
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Overview

  • The MI350X and MI355X deliver up to four times more AI compute performance and 35 times faster inference than the MI300X series.
  • Built on CDNA4 architecture with TSMC’s 3nm process, the GPUs feature up to 288GB of HBM3E memory and 8 TB/s of memory bandwidth.
  • AMD asserts the MI355X outpaces Nvidia’s Blackwell B200 in key AI tests such as Llama 3.1 405B inference by up to 1.3×.
  • Oracle Cloud Infrastructure, Meta and Microsoft have begun deploying MI350 GPUs for AI training and inference in their data centers.
  • AMD has acquired 25 AI-focused companies in the past year to bolster its chip ecosystem and enhance the ROCm software stack.