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Alveus Therapeutics Launches With $159.8 Million Series A to Advance Durable Obesity Treatments

The startup targets longer-lasting weight control with programs built for maintenance, tolerability and healthier body composition.

Overview

  • The round was led by New Rhein Healthcare Investors, Andera Partners and Omega Funds, with Sanofi Capital, Kurma Partners and Avego BioScience Capital participating.
  • Andera’s Jan Van den Bossche and Omega Funds’ Claudio Nessi are joining the board of directors.
  • Proceeds will fund Phase 2 development of ALV-100, a bifunctional GIPR antagonist and GLP-1 receptor agonist designed for durable weight loss with less frequent dosing.
  • Alveus is preparing IND submissions for early programs including ALV-200, a selective amylin receptor 3 peptide agonist described as entering IND‑enabling or regulatory filing stages.
  • Headquartered in Philadelphia with R&D in Copenhagen, the company is led by CEO Raj Kannan and senior executives with prior obesity and metabolic drug experience at Novo Nordisk and Eli Lilly.