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Alabama–Vanderbilt Rematch Returns to Bryant-Denny on Saturday

Undefeated Vanderbilt, led by Diego Pavia, enters under a roughly 10-point Alabama line with College GameDay elevating the stage.

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Will Ty Simpson and the Alabama Crimson Tide beat the Vanderbilt Commodores on Saturday? SEC football predictions, picks, odds preview the college football Week 6 game on Oct. 4, 2025.
Diego Pavia #2 of the Vanderbilt Commodores runs the ball during the second half against the Georgia Tech Yellow Jackets in the Birmingham Bowl at Protective Stadium on December 27, 2024 in Birmingham, Alabama.
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Overview

  • No. 11 Alabama hosts No. 17 Vanderbilt at 2:30 p.m. CT on ABC at Bryant-Denny Stadium.
  • The Commodores beat then-No. 1 Alabama 40-35 in 2024, their first win over the Tide since 1984.
  • Pavia said, "If we play our game, it won't be close," after a 5-0 start featuring 1,211 passing yards and 13 touchdowns.
  • Alabama quarterback Ty Simpson, coming off a road win at Georgia, described the team’s approach as "Alabama against everybody."
  • Vanderbilt’s defense allows 17.2 points per game with DE Miles Capers leading the SEC in tackles for loss, and Johnny Manziel plans to support Pavia from the Commodores sideline.