AI Tool Improves Detection of Epilepsy-Linked Brain Lesions Missed by Radiologists

The MELD Graph software identifies subtle brain abnormalities, potentially enabling earlier diagnosis and better treatment for drug-resistant epilepsy.

• MELD Graph, an AI-powered tool developed by King's College London and UCL, detects 64% of epilepsy-linked brain lesions missed by radiologists.
• The tool focuses on identifying focal cortical dysplasia (FCD), a common cause of drug-resistant epilepsy often treatable with surgery.
• Researchers trained the AI using MRI data from 1,185 patients across 23 epilepsy centers worldwide, including 703 with FCD, half of whom were children.
• The technology could reduce diagnostic delays, improve surgical outcomes, and save healthcare systems significant costs, such as up to £55,000 per patient for the NHS.
• Although not yet clinically available, MELD Graph has been released as open-source software, with workshops underway to train clinicians globally.

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