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AI-Powered STAR System Delivers First Pregnancy for Azoospermic Couple

The couple is expecting in December following Columbia researchers’ use of AI to isolate viable sperm unseen by embryologists.

As artificial intelligence shapes fertility care, it’s now helping doctors at Columbia University Fertility Center find hidden sperm.
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Overview

  • The couple had endured 15 unsuccessful IVF cycles over 18 years before turning to Columbia’s AI solution.
  • STAR (Sperm Track and Recovery) combines a proprietary fluidic chip with machine learning to detect and extract sperm from samples with near-zero counts.
  • In validation tests, STAR located 44 sperm in an hour in a sample that embryologists had declared sperm-free after two days.
  • During the March procedure, the system identified three viable sperm used in IVF to create an embryo that led to the ongoing pregnancy.
  • Columbia University Fertility Center plans to publish its findings and is exploring partnerships to extend STAR’s availability to other clinics.