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AI-Powered CREME Revolutionizes Virtual Gene Editing

New tool developed by Cold Spring Harbor Laboratory allows scientists to simulate thousands of gene perturbations, paving the way for groundbreaking genetic research.

  • CREME, an AI-powered virtual laboratory, enables geneticists to conduct thousands of virtual gene-editing experiments quickly and efficiently.
  • The tool is inspired by CRISPR interference (CRISPRi) and allows for the simulation of gene activity changes in a virtual genome.
  • Researchers at Cold Spring Harbor Laboratory, led by Assistant Professor Peter Koo, have utilized CREME to gain insights into gene regulation rules.
  • CREME's capabilities were tested on another AI genome analysis tool, Enformer, revealing valuable genetic rules that could aid in drug discovery.
  • The virtual nature of CREME allows scientists without access to physical labs to participate in advanced genetic research, potentially leading to new therapeutic targets.
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