AI-Powered CREME Revolutionizes Virtual Gene Editing
New tool developed by Cold Spring Harbor Laboratory allows scientists to simulate thousands of gene perturbations, paving the way for groundbreaking genetic research.
- CREME, an AI-powered virtual laboratory, enables geneticists to conduct thousands of virtual gene-editing experiments quickly and efficiently.
- The tool is inspired by CRISPR interference (CRISPRi) and allows for the simulation of gene activity changes in a virtual genome.
- Researchers at Cold Spring Harbor Laboratory, led by Assistant Professor Peter Koo, have utilized CREME to gain insights into gene regulation rules.
- CREME's capabilities were tested on another AI genome analysis tool, Enformer, revealing valuable genetic rules that could aid in drug discovery.
- The virtual nature of CREME allows scientists without access to physical labs to participate in advanced genetic research, potentially leading to new therapeutic targets.